Diethyl Ethylphosphonate

Diethyl Ethylphosphonate

    Specifications
    HS Code 525659
    Chemical Formula C6H15O3P
    Molar Mass 166.155 g/mol
    Appearance Colorless liquid
    Odor Faint, characteristic odor
    Density 1.009 g/cm³ at 20 °C
    Boiling Point 187 - 188 °C
    Melting Point -70 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 76 °C

    As an accredited Diethyl Ethylphosphonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Diethyl Ethylphosphonate in 5 - liter sealed plastic containers for safe storage.
    Storage Diethyl ethylphosphonate should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent fire risks. It should be kept in a tightly - sealed container to avoid evaporation and contact with moisture, which could potentially cause hydrolysis. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions.
    Shipping Diethyl ethylphosphonate is shipped in accordance with strict chemical regulations. It's typically packaged in corrosion - resistant containers, secured to prevent leakage, and transported by carriers trained in handling hazardous chemicals, ensuring safe transit.
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    Diethyl Ethylphosphonate Diethyl Ethylphosphonate
    General Information
    Historical Development
    Diethyl Ethylphosphonate is a fine chemical product. Its first work was made in the late 19th century. Western scholars explored changes in the structure of phosphate esters and gradually obtained its method. By the 20th century, war and agricultural and commercial needs were carried out simultaneously, and scientific research became more and more refined. Chemical companies adopted modern synthesis techniques to react alcohol and phosphorus to produce Diethyl Ethylphosphonate, which increased its purity. Its physical properties are stable and it is widely used in organic synthesis, flame retardants and pharmaceutical excipients. With the progress of science and technology, purification and purification technologies are more refined, and the quality is getting better. Today, the world's transportation is convenient and the supply and sales are smooth. This product is used in both China and the West, and it is in its heyday. Looking back on its changes, from laboratory preparation to industrial-scale mass production, human intelligence and ingenuity have been indispensable.
    Product Overview
    Diethyl ethyl phosphonate, chemical formula C6H15O3P, light yellow in color and clear in liquid form. Its stability, slightly special odor, insoluble in water, easily soluble in organic solvents such as alcohol ether. As one of the organophosphorus esters, it is widely used in medicine, pesticides, flame retardants and organic synthesis, and is also the first choice for the synthesis of various organic intermediates. The preparation method is usually obtained by reacting ethanol and triethyl phosphonate. Its product has high purity and few side reactions, making it easy to produce on a large scale. For storage and transportation, it should be sealed and cool to avoid high temperature open flames, and it should not be stored for a long time or change in case of moisture. It is widely used and has excellent performance, and is reused in modern chemical industry.
    Physical & Chemical Properties
    This substance is called ethyl diethyl phosphonate. Its color is like a colorless transparent liquid, and the gas is slightly aromatic. It is slightly soluble in water, but soluble in organic solvents such as alcohols and ethers. The boiling point is as high as 215 to 217 degrees Celsius, and the density is about 1.01-1.02 per cubic centimeter. The viscosity is low, and the flow is easy. The refractive index is between 1.408 and 1.414. It is stable at room temperature and pressure. It can slowly release the reaction in case of strong oxidants or strong acids. It has a high ignition point and is not easy to spontaneously ignite. The vapor is slightly irritating, and it can be flammable in case of an open flame. When burned, phosphorus oxides and other toxic fumes will escape. It is chemically mild. It needs to be dried away from light and kept away from fire sources. It is often used as a phosphorus-containing organic intermediate and is also a raw
    Technical Specifications & Labeling
    The product name is ethyl diethyl phosphonate. Its shape is clear liquid, colorless and slightly special gas, stable properties, and not easy to evaporate at room temperature. Molecular formula C6H15O3P, molecular weight is 182.16. Boiling point 197-200 degrees Celsius, density is about 1.021 to 1.029 g/cm ³, refractive index is 413-1.417. Solubility is better than most organic solvents, slightly soluble in water. The content is as much as 99.0% or more, and there are very few impurities. Packaging is mostly used in plastic drums with a net weight of 25 kg, sealed storage, protected from light and moisture, and placed in a cool and ventilated place. Transportation needs to be protected from sun exposure, high temperature and leakage. Appearance, batch number, net weight, production date and main technical parameters are listed on the container logo.
    Preparation Method
    In the preparation of ethyldiethylphosphonic acid ester, the raw materials are mostly phosphorus trioxide, anhydrous ethanol and bromoethane. First, phosphorus trioxide is slowly dissolved in ethanol, and the temperature should be controlled moderately to prevent unconsciousness. Then bromoethane is added dropwise to make it interact with phosphorus trioxide and ethanol. With the help of catalysts such as sodium hydroxide, hydroxide ions promote the dehydrogenation of alcohol groups and help to form phosphonate intermediates. Then, the reaction solution is stirred at constant temperature. After the reaction is completed, the by-product hydrogen bromide is precipitated, and it must be removed by alkaline method. Finally, the obtained mixture is purified by vacuum distillation to separate the remaining impurities. Its catalytic mechanism is that hydroxide ions activate ethanol, enhance nucleophilicity, promote the combination with phosphonoxy, and then react with halogenation to produce the desired product. In this way, ethyl diethyl phosphonate is purified.
    Chemical Reactions & Modifications
    Diethyl ethyl phosphonic acid ester is a phosphonic acid ester organic substance with clear properties and a slight aroma. When it encounters strong bases or strong acids, it is easy to hydrolyze into phosphonic acids and alcohols, and can also be self-polymerized or cracked at high temperatures. React with halogenated alkanes, and by catalysis, it can replace to form various phosphonic acid ester derivatives; when it encounters aramid or alcohols, it is supplemented by condensation agents, and it is easy to form phosphonamides or phosphates. If it is under basic or metal cation conditions, its molecular structure is excited, and the substituent group is also easy to migrate. The application of modification can be oxidized into phosphonates to enhance its flame retardant or chelating properties; or various functional groups can be derived by reduction and alkylation methods for the synthesis of rocket propellants, new flame retardant materials and organic synthesis intermediates. From this perspective, this phosphate ester has many reaction pathways and wide modification space, making it an essential product for polymer materials and fine chemistry.
    Synonyms & Product Names
    Diethyl ethylphosphonate is one of the organophosphorus compounds. There are many synonyms, or ethyl diethyl phosphonate, or ethyl diethyl phosphate, all of which follow the name change. And its English name is Diethyl ethylphosphonate, also known as Diethyl ethylphosphonate, or simply recorded as DEEP, the chemical number is 78-38-6, and the CAS number is often found in the merchant's book. In the Western Pharmacopoeia, or see Phosphonic acid, ethyl-, diethyl ester; circulation between trade, all companies have registered trade names, but the quality is the same. There are also general trade names such as Et diethylphosphonate, DEEP, Diethyl ethylphosphonate liquid, which are actually called one thing. The size and purity of the packaging are slightly different when purchasing and selling in the market, but the name and nickname of the product have not changed much. Where the academic research is conducted, it is advisable to incorporate different names to prevent confusion between experimentation and purchase.
    Safety & Operational Standards
    Diethyl Ethylphosphonate, chemicals are also used. The properties are clear, colorless, slightly odorous, soluble in alcohol ether, insoluble in water. Its material is flammable, and it will be dangerous to vaporize in case of hot topics or open flames, and there is a risk of intense reaction in case of strong oxidants. It is to be stored, transported and operated with strict caution. Storage should be in a cool and ventilated room, away from fire sources, and should not be mixed with strong oxidants such as nitric acid and peroxide. When unsealing, use gloves, goggles and barrier work clothes to defend yourself against muscle damage. Be sure to seal it after use to prevent leakage and volatilization, pollute the air, and cause inhalation and harm. If there is leakage, it should be covered with an adsorbent immediately to rush water to prevent spread. Disposal of residues should be handled in accordance with the specific specifications of the organophosphorus category. Do not discard them in natural water bodies and sewers to avoid ecological damage.
    In workplaces, there should be good ventilation and ventilation facilities to prevent vapor accumulation. Operators must be specially trained to be familiar with its hazards and first aid methods. If it touches the skin, wash it with water and soap immediately, and change the dye and clothing as soon as possible. If it splashes into the eye, rinse it thoroughly with clean water urgently and go to the doctor immediately. Those who inhale its gas should be transferred to a place of fresh air, and given oxygen or medical treatment if necessary. It is forbidden to eat and drink in the operation area. Before leaving the post, you must clean your hands and prevent the import of chemicals. Regularly check the content of it in the air to prevent excessive harm to health. In case of fire, it is advisable to use dry powder and carbon dioxide fire extinguishers, and do not use water to spray, because it can make the chemical reaction worse and increase the harm. Waste is collected in a covered container and marked with a hazardous label. Only by observing this safety and norms can you be safe from harm, operate safely, and protect your health.
    Application Area
    Diethyl Ethylphosphonate, chemically stable, soluble in a variety of organic solvents, has a wide range of uses. In organic synthesis, it is often used as a phosphate ester intermediate, which can be used in the development of drugs, pesticides and flame retardants. It participates in the Arbuzov reaction and can synthesize a variety of phosphorus-containing functional materials, especially catalysts, interface agents and precursors of bioactive molecules. It can also be used for the modification of polymer materials to give products heat resistance and flame retardant properties. In the field of medicine, it is mostly used as a raw material to participate in the preparation of anti-tumor and antibacterial drugs. In the agrochemical industry, it is used as an important building block for herbicides and insecticides. In industry, it can also be formulated as an extractant or metal extractant to improve the efficiency of separation and purification. Overall, its applications cover medicine, agrochemistry, new polymer materials and functional additives, with significant potential and promising prospects.
    Research & Development
    Diethyl Ethylphosphonate is a fine chemical product. It is mild in nature and has a wide range of applications. Modern scientists are dedicated to the research and development of this product. The sages tried to use multiple synthesis methods to explore its reaction mechanism, and they have benefited a lot. In the laboratory, either Ethylphosphonic acid is used as raw material or ester exchange method is produced, which is unique. Many improved methods have been developed, and the purity and yield of the finished product have been significantly improved. Today, this product is widely used in organic synthesis, flame retardants and pesticides, helping to innovate new materials and promote the progress of high-tech industries. However, its safety and environmental protection issues are also the focus of scholars' attention. One after another, green synthesis is explored to reduce by-products. If both efficiency and environmental protection can be taken into account, it will be a great help for the chemical industry. It is better to retreat and focus on research, and its prospects are broad.
    Toxicity Research
    Diethyl Ethylphosphonate is one of the substances used in today's chemical processes. Examine its shape, colorless liquid, and slightly peculiar odor. If you are not careful, it may be harmful. It is taken into the body and ingested orally, which can cause gastrointestinal discomfort, vomiting and diarrhea, fatigue and headache, infiltrate the skin, or cause redness, swelling and pain. If its volatile gas is inhaled, the respiratory tract is easily involved, causing coughing, wheezing and other diseases. Exposure for a long time can damage the liver and kidneys, or even involve the nerves. Animal tests, those with severe doses are at risk of nerve paralysis and even death. However, with proper protection and standardized disposal, the harm is controllable. Anyone who handles this medicine must have gloves, protective clothing, and goggles to avoid contamination; the workplace is well ventilated, and inhalation is safe. Finally, although Diethyl Ethylphosphonate is a weapon, it should be used with caution, and its harm can be avoided.
    Future Prospects
    Phenethyl ethyl phosphonate is mild in nature and widely used. Today's science is changing with each passing day, and the development of many new materials and new drugs relies on this product. With its stable properties and excellent flame retardant properties, it has been widely used in polymer materials, pharmaceutical synthesis, fire retardant coatings and other fields. In the future, the process will be more advanced and the purity will be improved, and the development of derivatives will also come into being. With the trend of global green environmental protection, the synthesis of low toxicity and low pollution will be accelerated. International cooperation is becoming more and more frequent, and technical exchanges are becoming common. It is foreseeable that its market demand will rise steadily, and innovative uses will emerge in an endless stream. It will definitely lead the development of the industry, benefit society and benefit mankind.
    Where to Buy Diethyl Ethylphosphonate in China?
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    Frequently Asked Questions

    As a leading Diethyl Ethylphosphonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Diethyl Ethylphosphonate?
    Diethyl Ethylphosphonate is an organic phosphorus compound in chemistry. Its molecular formula is C6H15O3P. If this substance has no color, taste slightly bitter, dissolves in a variety of organic solvents, and has good thermal stability. Since the 20th century, scholars have widely studied it for its unique functions in organic synthesis and materials science. Its main uses have several ends, all of which are related to industrial use.
    First, it is used as an intermediate for organophosphorus pesticides and drugs. Due to the development of phosphorus ester chemistry, many important chemical drugs are based on phosphonates. Diethyl Ethylphosphonate can provide phosphorus during the synthesis process and adjust the molecular structure to make it biologically active. Such as herbicides and pesticides, it is often used as a raw material and further transformed to obtain the expected active substance. In the pharmaceutical industry, its phosphine-based properties are also used to synthesize antibacterial and antitumor lead compounds for exploring new fields of pharmacology.
    Second, it is a nucleophilic reagent commonly used in organic synthesis reactions. It is widely used in new carbon-carbon bond coupling technologies such as Michael addition and Horner-Wadsworth-Emmons reaction. With its phosphonate ester structure, it can stabilize reaction intermediates, improve synthesis efficiency, simplify steps, and reduce side reactions. Scholars use it to prepare a variety of unsaturated compounds, or fine-tune the stereoselectivity of products, which is helpful for the development of high-value pharmaceutical molecules and functional materials.
    Third, it is used in the synthesis of flame retardant materials. Phosphonate is a well-known flame retardant component. Adding Diethyl Ethylphosphonate to a polymer or resin system can significantly improve its heat resistance and flame retardant properties. In industry, polymers are often modified with such compounds, which are used in electronics, building materials, aviation and other fields to enhance the safety and life of products.
    It is also complexed with metal ions for extraction and separation, and is used in metallurgy and environmental protection engineering. Looking at its uses, Diethyl Ethylphosphonate has won the attention of the scientific and technological community as a hub of chemical synthesis, an auxiliary agent for functional materials, and a raw material for industrial modification. Its use promotes the continuous progress of organophosphorus chemistry and shows the wisdom of human beings in regulating material properties.
    What are the chemical properties of Diethyl Ethylphosphonate?
    Diethyl Ethylphosphonate is also a chemical. Its molecular formula is C6H15O3P, and its structure is phosphate ester. The main skeleton is connected by one phosphorus atom and three oxygen atoms, two of which are connected to ethyl, and the rest is ethylphosphorus. Its color is colorless, and it is often a transparent liquid with a slightly sweet taste and good volatility.
    It is mild in nature and non-flammable when heated. However, it can decompose under high temperature and release toxic fumes. It is soluble in most organic solvents such as alcohols, ethers, esters, etc., and its solubility in water can also be observed. Phosphate bond, not easy to hydrolyze, but under the action of strong acid or strong base, it can be broken into corresponding alcohol and phosphoric acid products. In case of strong oxidants such as potassium permanganate, it can be oxidized. It can also react with strong reducing agents, but its activity is not as good as that of strong oxidizing agents. Under the action of hydride, it can be partially reduced to trivalent phosphorus compounds.
    The reactivity of this substance is slightly weaker than that of phosphoric acid or diethyl phosphate, but it has ethyl substitution on phosphorus, and the electron cloud distribution is relatively uniform, so it makes its molecules stable and not easy to decompose spontaneously. However, if it is co-heated with nucleophiles such as alcohols and amines, it can perform a replacement reaction to generate new phosphates or phosphoramides. In addition, if it exists as a halogenated hydrocarbon, it can be used as a nucleophilic agent for Michael addition to generate new compounds with C-P bonds. It can also be used as a raw material for various phosphate ester derivatives or phosphonate drugs.
    In organic synthesis, it is often used as a phosphite ester provider, because its phosphorus atom has a double-bond electron pair that can produce nucleophilicity. It can participate in phosphorus-related organic reactions such as Wittig reaction, and then be used in the synthesis of various organic products such as olefins. It is an important synthetic intermediate and is widely used in pesticides, medicine and many other fields. Its toxicity is lower than that of organophosphorus pesticides, but long-term exposure also poses health risks, so pay attention to protection.
    In summary, the chemical properties of Diethyl Ethylphosphonate are mild and stable, acid and alkali resistance, soluble in multiple organic solutions, and can react with various nucleophiles and some metal ions. It is an important member of organophosphorus chemistry.
    What are the storage and transportation requirements for Diethyl Ethylphosphonate?
    Diethyl Ethylphosphonate is an organophosphorus compound. It is stable in nature and has a certain volatility. When it comes to hot topics, it is easy to decompose and produce toxic vapors. Storage and transportation, we must be cautious to prevent problems before they occur. The main points are as follows:
    When storing this substance, it must be stored in a closed container to prevent vapor from escaping. The container material should be glass, enamel or sealed plastic. Do not expose metal to prevent corrosion. Store in a ventilated and cool place, away from fire sources, heat sources, and all flammable materials. Store in isolation from acids, strong alkalis and oxidants, and must not be stored in the same room. The indoor temperature should always be lower than normal temperature, and the humidity should not be too high. The warehouse must be equipped with good ventilation equipment to avoid evaporation and deterioration of high temperature and humidity. In summer, special cooling measures should be added. The storage area shall be marked with a warning label indicating its harmful characteristics to alert the operator.
    During transshipment, it must be handled lightly to prevent impact and dumping to avoid damage and leakage of the container. Vehicles and ships shall have good ventilation conditions and shall not be mixed with food, medicine and daily necessities. Before departure, check the safety of the container seal and whether there is any risk of leakage. During transportation, prevent rain, sun exposure and heavy pressure. In case of leakage, it should be quickly covered with fine sand or inert adsorbent. After collection, it should not be discarded in sewers and the natural environment. Beware of pollution.
    To operate this object, the staff must have protective hats, gloves and goggles. The operation room is equipped with flushing equipment. If it accidentally splashes on the skin or eyes, rinse with running water quickly, and send it to the medical office if you feel unwell. Unrelated personnel are strictly prohibited from entering the storage place, and idle utensils should not be stacked at will.
    In summary, the storage and transportation of Diethyl Ethylphosphonate depends on airtight, heat-proof, light-proof, ventilation, and beware of leakage and mixing to ensure safety. In this way, the storage and transportation methods can be guaranteed, and personal and property are safe.
    What is the impact of Diethyl Ethylphosphonate on the environment?
    Diethyl Ethylphosphonate, a chemical substance, is widely used in organic synthesis and pesticide manufacturing. Its properties are colorless liquid, with a slight odor. If this substance penetrates into the environment, it has a lot of impact and cannot be ignored. It flows in soil and water bodies, easily migrates with water, polluting rivers and lakes. It can also accumulate in the soil through adsorption, and over time it will affect the growth of crops. Its chemical properties are relatively stable, and it is not easy to degrade naturally. In the environment that persists, the accumulated harm is difficult to eliminate quickly.
    In water bodies, Diethyl Ethylphosphonate is classified as organic phosphorus, which can easily cause adverse effects on plankton and fish in the water. If the concentration is too high, the enzymes in the organism will react with the chemical substances, which will hinder their physiological activities or cause death. What's more, it can be passed through the food chain, causing harm to higher organisms and affecting the ecological balance. If humans and animals accidentally ingest contaminated water or food, it can cause nausea, headache, and nerve damage, and the consequences will be endless. Today's treatment, if the water body is polluted, it is not easy to control, and it requires a combination of technologies, which consumes manpower and financial resources.
    This substance is commonly found in agricultural production, and its waste may be discharged at will due to poor management, which is easy to cause environmental damage. If there is escape in the air, although the concentration is not high, it can accumulate in the body for a long time, causing chronic poisoning. The boundaries between cities and rural areas are difficult to guarantee. Ordinary sewage treatment facilities have limited removal efficiency for such organic phosphides, and there is a risk of entering public water sources. Today, environmental protection legislation has placed strict restrictions on its use and emissions, but if chemical companies and agricultural applicators fail to strictly abide by the regulations, the environment will still be affected by it.
    According to scientific research, Diethyl Ethylphosphonate has a slow degradation rate and is easy to accumulate in soil and water bodies, laying hidden dangers. To protect the ecology, we must use such chemicals with caution, keep pace with the times, improve treatment technology, and establish a monitoring system for long-term peace. If we ignore its harm, we will eventually suffer the consequences and endanger human beings and all living things. "Yi" said, "A house that builds up good will have more than celebration; a house that builds up bad will have more disaster." Warning words, must not be ignored.
    What are the safety precautions for Diethyl Ethylphosphonate?
    Diethyl Ethylphosphonate, chemical products are also flammable, and there is a risk of burning in case of high temperature or open flame. Be careful when operating, and avoid negligence. At the beginning, its storage must be in a cool and ventilated place, away from fire sources and heaters, and do not mix with oxidants, strong acids and alkalis. The container should be sealed for fear that its odor will escape and cause poisoning.
    When using it, goggles, chemical-resistant gloves, and laboratory clothes should be prepared to avoid direct contact with the skin, eyes and skin. Operators must be knowledgeable, and non-professionals should not approach. If liquid droplets splash on the eyes or skin, they should be urgently washed with water, and those who are still difficult to recover should be sent to medical treatment. In the place of operation, a fume hood is appropriate, so that the gas can escape completely.
    Between dumping and removal, walk slowly and carefully, do not spill. If there is a spill, use an inert adsorbent such as dry sand and activated carbon to quickly suck, and discard it in a special place. Do not dispose of it at will to avoid damage. Waste liquid must also be treated according to chemical waste procedures, and it is forbidden to burn and discard in sewers.
    In case of fire, treat it with dry powder and carbon dioxide fire extinguishers. Avoid water to fight, so as not to spread or cause secondary reactions. In the event of a fire, the operator should wear a self-contained breathing apparatus to quickly evacuate unrelated people. If there is odor, quickly increase ventilation and evacuate immediately.
    Long-term contact can damage human nerves and internal organs. Gas or vapor inhalation, or can cause dizziness, nausea, fainting, be sure to leave the contaminated place in time. Use it to clean your hands and face, do not eat or drink in the operating place, and avoid contamination by other things.
    Its chemical activity is active, and it may react violently in case of strong oxidants. When using it, it is necessary to find out its compatibility. The bottle label and instructions are detailed in the easy-to-see place to warn against misuse and misperceptions.
    In short, be in awe of its danger, abide by the rules, and protect properly, so that you can keep your person safe and the experiment smooth and stable.