Product Name: Diethyl Ethylphosphonate
Chemical Formula: C6H15O3P
Synonyms: Ethylphosphonic acid, diethyl ester
Recommended Use: Intermediate for organic synthesis
Supplier: [Company Name, Address, and Contact Details]
Emergency Contact: [Local Emergency Number]
GHS Classification: Flammable liquids (Category 3), Acute toxicity from oral exposure (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, harmful if swallowed, causes skin and eye irritation
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat and open flames; avoid inhalation, skin, and eye contact; wear protective gear; avoid eating, drinking, or smoking during use
Chemical Name: Diethyl Ethylphosphonate
CAS Number: 78-38-6
Concentration: 98–100%
Impurities: Trace phosphorus-based byproducts, low levels of ethanol or unreacted precursors possible
Inhalation: Move person out of the area into fresh air right away; seek medical attention if coughing, breathing issues, or dizziness occur.
Ingestion: Rinse mouth out with water; do not induce vomiting; contact emergency services or poison control.
Skin Contact: Rinse skin with soap and water for several minutes; remove contaminated clothes; get medical advice if skin redness or pain persists.
Eye Contact: Flush eyes with lukewarm water for 15 minutes, keeping eyelids apart; consult an eye specialist in case of irritation or blurred vision.
Most Important Symptoms: Throat and lung irritation, skin redness, nausea, vomiting, headache.
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam.
Unsuitable Extinguishing Media: Water jet (risk of spreading fire).
Hazardous Combustion Products: Phosphorus oxides, ethyl fragments, carbon monoxide, carbon dioxide.
Special Protective Equipment: Firefighters use full protective clothing and self-contained breathing apparatus.
Specific Fire Fighting Methods: Cool neighboring containers by spraying with water, avoid runoff into drains.
Personal Precautions: Clear area, ventilate space, keep non-emergency staff away, use chemical splash goggles, nitrile or neoprene gloves, flame-resistant clothing.
Environmental Precautions: Prevent discharge into soil, drains, or waterways; use barriers to contain liquid spill.
Spill Cleanup Methods: Absorb liquid with adsorbent material (vermiculite, sand); collect in closed containers for proper disposal; clean surfaces with detergent; ventilate area after cleanup.
Handling: Use in ventilated space, avoid sources of ignition, keep containers tightly closed after use, ground and bond containers for transfers to avoid static.
Storage: Store in cool, dry, well-ventilated spot, away from heat and direct sunlight; separate from strong bases, oxidizers, and acids; use containers made for flammable chemicals; keep in original packaging or compatible drums.
Special Notes: Label storage areas, check for leaks regularly, keep emergency response kits nearby.
Exposure Limits: No official OSHA or ACGIH exposure limits; general guidelines for organic phosphonates suggest minimizing exposure.
Engineering Controls: Chemical fume hood, general mechanical ventilation, explosion-proof electrical systems.
Personal Protection: Safety goggles, flame-resistant lab coat, chemical-resistant gloves (nitrile, butyl rubber), splash-proof face shield, respirator during large-scale handling.
Hygiene Practices: Wash hands after handling, avoid skin contact, keep contaminated clothing off premises.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, organic phosphorus-like scent
Odor Threshold: Not established
pH: Neutral to slightly acidic
Melting Point: -55°C
Boiling Point: 206–208°C
Flash Point: 87°C (closed cup)
Evaporation Rate: Slow
Flammability: Flammable
Upper/Lower Flammability Limits: Not specifically established
Vapor Pressure: Low (approx. 0.02 mm Hg at 20°C)
Vapor Density: Heavier than air
Density: 1.055–1.065 g/cm³ at 20°C
Solubility: Miscible with organic solvents, slightly soluble in water
Partition Coefficient (log Kow): Estimated 0.5–1.2
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 230°C
Chemical Stability: Remains stable at room temperature if kept away from heat, sparks, and direct sunlight.
Reactivity: Not highly reactive, but decomposes fast under strong acids or bases, generating flammable or toxic vapors.
Incompatible Materials: Strong oxidizers (nitric acid, peroxides), concentrated alkalis, strong acids.
Hazardous Decomposition Products: Phosphorus oxides, ethylene, possible toxic vapors.
Polymerization: No hazardous polymerization expected.
Likely Routes of Entry: Ingestion, inhalation, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 3600 mg/kg; Inhalation: data limited, irritation expected.
Skin Corrosion/Irritation: Causes moderate irritation after contact.
Serious Eye Damage/Irritation: Leads to redness, pain, possible blurred vision.
Respiratory Effects: Shortness of breath, coughing possible.
Chronic Effects: No clear evidence of long-term effects except for possible skin sensitization.
Carcinogenicity/Mutagenicity: Not classified as carcinogen or mutagen by IARC, NTP, OSHA.
Reproductive Toxicity: No strong evidence, data limited.
Other Notes: Individuals with respiratory or skin conditions should avoid exposure.
Toxicity to Aquatic Life: Expected low acute toxicity (EC50 in algae/fish >100 mg/L, estimated).
Persistence/Degradability: Likely to degrade under environmental conditions, but may persist briefly in soil.
Bioaccumulation Potential: Low (low log Kow, rapid metabolism in biota).
Mobility in Soil: Mobile in sandy soils due to water solubility; avoid runoff.
Other Harmful Effects: No evidence for long-lasting biohazard, but should avoid large-scale spills into waterways.
Waste Treatment Methods: Take liquid waste to licensed disposal specialist; do not pour into sewer, streams, or public water supplies.
Packaging Disposal: Rinse empty containers with solvent, triple rinse if possible, then dispose of as chemical waste.
Contaminated Materials: Bag up gloves, wipes, rags, and contaminated disposables as hazardous waste.
Universal Waste Codes: Refer to local and national waste disposal codes for organophosphonates.
Environmental Caution: Incineration preferred for large amounts; follow all local, regional, and national waste regulations.
UN Number: 3272
UN Proper Shipping Name: Esters, organophosphorus, n.o.s. (includes Diethyl Ethylphosphonate)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III (minor hazard within its class)
Marine Pollutant: Not regulated as a marine pollutant
Special Precautions: Use spill-proof containers, proper labeling, keep upright and secure during shipments, avoid exposure to heat sources during transport.
Transport Labels: Flammable liquid, UN 3272
OSHA: Considered hazardous under Hazard Communication Standard (29 CFR 1910.1200).
TSCA: Listed in U.S. Toxic Substances Control Act inventory.
REACH: Registered or pre-registered as required for import into the EU.
SARA Title III: Not subject to Section 302, 304, or 313 major thresholds, but reportable as a hazardous chemical.
WHMIS Classification (Canada): B3 (Combustible Liquid), D2B (Toxic Material causing other toxic effects).
California Proposition 65: Not on the list of chemicals known to cause cancer or reproductive harm.
Other Global Regulations: Keep up with local harmonized classification and inventory, confirm any region-specific limits or banned uses.
