Product Name: Sodium Monofluorophosphate
Synonyms: MFP, Monofluorophosphoric Acid Disodium Salt, Sodium Fluorophosphate
Chemical Formula: Na2PO3F
Molecular Weight: 143.95 g/mol
Chemical Family: Inorganic phosphate compound
Recommended Use: Toothpaste ingredient, dental products, oral care formulations
Manufacturer Contact: Supplier addresses and hotlines located on commercial packaging or safety data repositories
Emergency Contact: Chemtrec 24-hour Emergency Service or local poison control centers
CAS Number: 10163-15-2
UN Number: 9148 (if regulated for transport)
Classification: Acute Oral Toxicity Category 4, Eye Irritation Category 2A, Specific Target Organ Toxicity (single and repeated exposure)
GHS Label Elements: Warning symbol with exclamation mark
Hazards: Harmful if swallowed, may cause irritation to eyes, skin, and mucous membranes; overexposure can affect central nervous system and kidneys
Potential Health Effects: Ingestion can cause nausea, vomiting, abdominal pain; inhalation of dust brings respiratory irritation; contact leads to eye redness and skin dryness
Routes of Exposure: Inhalation, ingestion, skin or eye contact
Environmental Hazards: Toxic to aquatic life if large amounts released
Precautionary Statements: Avoid dust formation; keep containers tightly sealed; use proper personal protection
Chemical: Sodium Monofluorophosphate
Concentration: Typically 98-100% for technical grade
Other Ingredients: Water or inert filler content below 2% for stabilizing industrial and commercial formulations
Impurities: Traces of fluoride compounds, phosphate, sodium salts as process contaminants
Eye Contact: Rinse cautiously with water for 15 minutes; seek medical advice if discomfort persists
Skin Contact: Wash with soap and water; remove contaminated clothing; consult doctor if rash or irritation continues
Inhalation: Move individual to fresh air; monitor breathing and seek medical attention for persistent symptoms
Ingestion: Rinse mouth thoroughly; seek immediate medical help; never induce vomiting unless directed by medical personnel
Advice for Doctor: Treat symptomatically, monitor for signs of fluoride poisoning, provide supportive care
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide (CO2), foam
Hazardous Combustion Products: Phosphorus oxides, sodium oxides, hydrogen fluoride
Firefighting Advice: Wear self-contained breathing apparatus and chemical protective suit; avoid inhaling fumes
Special Procedures: Cool exposed containers with water, prevent runoff from reaching waterways
Flash Point: Not flammable as a solid but decomposes to release toxic gases under intense heat
Personal Precautions: Use dust mask, safety goggles, chemical-resistant gloves; ventilate area
Environmental Precautions: Prevent entry into sewers or waterways; alert authorities if large spills occur
Cleanup Methods: Sweep or vacuum up without generating dust; transfer to labeled, sealed container for disposal
Decontamination: Wash spill area with water, avoid dry brushing that lifts dust; collect contaminated cleaning water for disposal according to regulations
Handling Practices: Use only in well-ventilated areas; avoid creating dust clouds; wear recommended personal protective equipment
Storage Conditions: Store in original packaging in cool, dry, well-ventilated area; keep away from acids, oxidizers, moisture
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hygiene Measures: Wash hands thoroughly after handling; avoid eating, drinking, or smoking near material
Storage Temperature: Maintain ambient to below 30°C; protect from direct sunlight and extremes of humidity
Engineering Controls: Use local exhaust ventilation to minimize airborne dust
Occupational Exposure Limit: OSHA PEL (as fluoride): 2.5 mg/m3 TWA
Personal Respiratory Protection: Approved particulate respirator for dust
Eye Protection: Chemical safety goggles or face shield
Skin Protection: Chemical-resistant gloves, long-sleeved work clothes
General Protection: Avoid direct contact; wash contaminated clothing before reuse
Monitoring: Regular air monitoring for fluoride levels in high-use industrial settings
Appearance: White, odorless crystalline powder or granular material
Odor: None
Odor Threshold: Not applicable
pH (10% in water): 6.5–8.0
Melting Point: 625°C (decomposes)
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Not flammable
Solubility: Soluble in water: approx. 10-12 g/100 mL at 25°C
Vapor Pressure: Not volatile at room temperature
Relative Density: About 2.5 g/cm3
Partition Coefficient (n-octanol/water): Not available
Evaporation Rate: Not applicable
Viscosity: Not applicable
Chemical Stability: Stable under standard conditions; decomposes above 625°C
Conditions to Avoid: Elevated temperatures, exposure to acids and bases
Incompatible Materials: Strong acids release toxic hydrogen fluoride gas; strong alkalis accelerate breakdown
Hazardous Decomposition Products: Hydrogen fluoride, sodium oxide, phosphorous oxides
Polymerization: Will not occur
Reactivity: Reacts with acids to release corrosive, toxic gases
Acute Toxicity (Oral): LD50 rat, 900 mg/kg
Skin Corrosion/Irritation: Mild irritant to skin after prolonged or repeated exposure
Eye Damage/Irritation: Moderate eye irritant, especially as dust exposure
Respiratory or Skin Sensitization: May cause irritation of respiratory tract
Chronic Effects: Prolonged overexposure to fluoride compounds leads to fluorosis, bone and kidney damage
Carcinogenicity: No direct evidence of carcinogenicity in humans
Mutagenicity/Teratogenicity: Not mutagenic or teratogenic based on available data
Target Organs: Teeth, bones, kidneys, central nervous system in cases of chronic exposure
Symptoms of Overexposure: Abdominal pain, vomiting, diarrhea, muscle weakness, confusion in acute poisoning cases
Ecotoxicity: Harmful to aquatic organisms, especially in concentrated spills
Aquatic Toxicity: LC50 (fish, 96 hr): 60–75 mg/L
Persistence and Degradability: Inorganic material; does not biodegrade, breaks down slowly in water to fluoride ions and phosphates
Bioaccumulation Potential: Low at environmental concentrations, but fluoride may accumulate in aquatic plants and animals over long term
Mobility in Soil: Highly soluble, mobile in water; can leach to groundwater
Other Adverse Effects: No known ozone depletion or global warming impact
Waste Treatment Methods: Collect and place in suitable, marked containers for approved chemical waste disposal
Disposal of Product: Dispose according to local/regional/national/international regulations
Disposal of Packaging: Rinse and dispose as non-hazardous waste if decontaminated; otherwise, treat as hazardous
Environmental Precautions: Avoid release to the environment, do not pour into drains or waterways
Recommended Method: Incinerate or landfill in accordance with chemical waste protocols
UN Number: 9148
UN Proper Shipping Name: Sodium Monofluorophosphate
Transport Hazard Class: Not classified as hazardous for transport in most regions
Packing Group: Not applicable for consumer grade; regulated in bulk industrial quantities
Marine Pollutant: Not specifically identified, but care recommended
Special Precautions: Keep containers tightly sealed, store upright, protect from moisture and mechanical shock
Transport Labels: None required for limited quantites, basic handling symbols for bulk shipping
OSHA Status: Regulated based on fluoride content
FDA Status: Permitted in over-the-counter dental preparations at controlled concentrations
TSCA Inventory: Listed
REACH Registration: Registered under European chemical safety legislation
SARA Title III: Not listed as a reportable substance
WHMIS Classification: Class D2B (Toxic Material Causing Other Toxic Effects) in Canada
Labeling Requirements: Chemical name and hazard warnings required on all containers
State Regulations: California Proposition 65: does not appear on Prop 65 chemical lists
Other International Inventories: Listed in AICS (Australia), DSL (Canada), NZIoC (New Zealand), IECSC (China), PICCS (Philippines), ENCS (Japan), ECL (Korea)
