Product Name: Triisobutyl Phosphate
Chemical Formula: C12H27O4P
CAS Number: 126-71-6
Product Use: Extraction solvent in chemical processes, flame retardant, antifoaming agent, plasticizer in industrial manufacturing
Synonyms: Phosphoric acid, triisobutyl ester
Supplier: Listed on container packaging, usually major chemical distributors and manufacturers
Emergency Contact: Locate on product label, includes 24-hour supplier-specific hotline
Physical Hazards: Clear, oily liquid with a faint odor, not classified as highly flammable, but emits toxic fumes in a fire
Health Hazards: Irritant to skin, eyes, and mucous membranes; Inhalation, ingestion, or skin absorption may lead to discomfort, headache, dizziness, nausea, or even more serious symptoms with extended exposure
Specific Hazards: Prolonged or repeated exposure leads to dermatitis or organ effects; large spills risk slippery floors and falls
Environmental Hazards: Spills may harm aquatic life due to lack of rapid biodegradation; runoff could affect water supplies or soil quality
Signal Word: Warning
Hazard Statement: May cause respiratory irritation and skin sensitization; avoid breathing vapors or direct contact
Chemical Name: Triisobutyl Phosphate
Concentration: ≥ 97% by weight (commonly available commercial purity)
Impurities: Small traces of isobutanol and phosphoric acid derivatives; check for manufacturer-specific details
Other Components: None intended or routinely present; consult batch-specific supplier paperwork for contaminants
Inhalation: Move to fresh air quickly, keep at rest, call for medical help if any discomfort surfaces or persists; oxygen or artificial respiration if breathing becomes difficult
Eye Contact: Flush both eyes gently with water for at least 15 minutes, lifting eyelids; remove contact lenses if possible, seek medical attention if irritation continues
Skin Contact: Wash affected skin with soap and water without delay, remove contaminated clothing, contact healthcare if redness, rash, or swelling develops
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek emergency medical support, provide information about the substance ingested
Symptoms: Redness, nausea, burning, headache, dizziness; possible delayed symptoms with prolonged or high-level exposure
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical powder, or carbon dioxide; water spray may help cool containers but won’t suppress fire alone
Unsuitable Media: Direct water jets can spread product but do not quench burning pools effectively
Specific Hazards: Burning TIBP forms toxic and irritating gases such as phosphorous oxides and carbon monoxide
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear
Fire-Fighting Procedures: Isolate hazard area, prevent runoff from fire control efforts from polluting waterways or sewers, fight fire upwind to avoid inhalation
Personal Precautions: Evacuate unprotected personnel, ventilate area, block access until cleanup finishes; wear gloves, safety goggles, and chemical-resistant clothing
Environmental Precautions: Avoid product spreading; do not allow product to reach drains, soil, or open water, use bunds or barriers around spills
Small Spill Cleanup: Absorb on inert material such as sand or earth, shovel into closed containers for disposal, wash area with soap and water
Large Spill Response: Call emergency responders, contain spill using dikes, pump out bulk liquid if possible, dispose of contaminated cleanup material as hazardous waste
Handling: Use only with adequate ventilation; avoid skin and eye contact; do not breathe vapors or mist; keep work area clean; cover containers when not in use
Safe Storage: Store in tightly closed, labeled containers in a cool, dry, well-ventilated area away from heat, sparks, open flame, and incompatible materials such as strong oxidizers
Storage Conditions: Temperature below 30°C; keep away from sources of ignition, acids, and strong bases
Advice on General Occupational Hygiene: Wash hands before eating, drinking, or using restroom; do not eat, drink, or smoke in handling area; change contaminated clothing and launder before reuse
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV for TIBP, use good practice to minimize exposure
Engineering Controls: Local exhaust ventilation recommended at points where vapors are generated; eye wash stations and safety showers within easy reach
Respiratory Protection: Use approved respirator if ventilation proves inadequate or risk of vapor inhalation exists
Eye/Face Protection: Chemical safety goggles or face shield
Skin Protection: Impervious gloves such as nitrile rubber or neoprene; full chemical-resistant clothing during bulk handling
Work Practice Controls: Keep work area uncluttered, ensure regular inspection and replacement of PPE, train workers on spill and exposure response
Appearance: Clear to pale-yellow, oily liquid
Odor: Slight ester-like odor
Boiling Point: About 282°C (539°F)
Melting Point: Below -80°C (-112°F)
Solubility: Practically insoluble in water; fully miscible with organic solvents (ethanol, ether)
Vapor Pressure: Low, less than 0.01 mmHg at 20°C
Density: 0.970 - 0.980 g/cm3 at 20°C
pH: Not measurable in water due to insolubility
Flash Point: 146°C (closed cup)
Autoignition Temperature: About 379°C
Partition Coefficient: Log Kow about 4.3, indicates heavy tendency to accumulate in organic phases
Viscosity: Approx. 9-11 mPa.s at 20°C
Chemical Stability: Stable under normal operating and storage conditions; long shelf life in closed containers
Reactivity: Does not react violently with common materials, reacts with strong acids and oxidizing agents to form hazardous products
Hazardous Decomposition Products: On combustion or decomposition, produces phosphorus oxides, carbon dioxide, carbon monoxide
Conditions to Avoid: Extreme heat, direct sunlight, open flames, sources of ignition, storage with incompatible chemicals mentioned above
Polymerization: Will not occur spontaneously under normal conditions
Acute Toxicity: Estimated oral LD50 (rat): 3200 mg/kg; skin absorption: >2000 mg/kg
Inhalation: Inhalation may lead to irritation of airways; higher concentrations or long exposure may affect central nervous system
Skin: Causes mild irritation, especially with unprotected repeat exposure
Eye: Moderate irritant, may cause redness, tearing, blurry vision
Chronic Effects: Prolonged contact hides risk of dermatitis, liver or kidney impact in experimental animals; reproductive studies inconclusive
Sensitization: Not known to cause allergic reaction in most people but individual sensitivity varies
Carcinogenicity: Not considered carcinogenic based on current ingredient evaluation
Ecotoxicity: Harmful to aquatic life, especially at high concentration; fish LC50 (96h): ~5-25 mg/L
Persistence and Degradability: Poorly biodegradable in water (biodegradation less than 10% in 28 days), persists for extended periods in soil or water
Bioaccumulative Potential: High for aquatic life due to strong log Kow, may build up in food chain
Mobility in Soil: Binds to organic matter, not likely to move far from spill site
Other Adverse Effects: Large spillage harms local habitat by smothering, oxygen depletion; extra caution near wetlands and drainage channels
Waste Disposal: Treat as hazardous industrial waste; incinerate in approved facility with flue gas scrubbing, consult national and local environmental authorities for disposal permits
Contaminated Packaging: Triple-rinse before recycling or disposal, segregate from food or feed use
Avoid Release: Do not pour into drains, natural water or soil; confirm cleanup with site monitoring
Disposal Methods: Solidify spilled liquid absorbent, pack in labeled drums for specialist firm pickup, maintain records of disposal batches and means
UN Number: Not classified as dangerous goods under most global transport regulations
Proper Shipping Name: Triisobutyl Phosphate
Class: Not regulated; check for supply blends with additives that might be regulated
Packing Group: Usually not assigned
Transport Hazard Labels: None required for neat product, affix standard chemical handling warnings
Special Precautions: Prevent container damage, spill containment on transport vehicle
Environmental Hazards: Avoid transport with foodstuffs, feed, or drinking water, alert transport staff to basic hazards
Inventory Listings: Appears on international chemical inventories such as TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia), ENCS (Japan)
Labeling Requirements: Warning symbol for irritant; GHS pictograms (exclamation mark, environment) as per national regulation
SARA Title III (USA): Not listed as an extremely hazardous substance
RCRA Waste Code: Not specifically listed; may become hazardous waste due to contamination
Canada WHMIS: Not specifically controlled, but safety precautions apply
REACH (EU): Pre-registered; manufacturers/importers document safety for all uses; end-users required to follow published guidance
Other Info: Employers keep safety records per OSHA 29 CFR 1910.1200; workers receive training on hazards, safe use practices, emergency procedures
