Product Name: Trimethyl Phosphate
Chemical Formula: (CH3O)3PO
CAS Number: 512-56-1
Synonyms: Phosphoric acid, trimethyl ester; Methyl phosphate, trimethyl
Manufacturer: [Insert specific supplier details for precise traceability]
Recommended Use: Chemical intermediate, solvent, plasticizer
Contact Information: [Supplier contact number, emergency line]
GHS Classification: Flammable liquid category 3, Acute toxicity oral category 4, Eye irritation category 2A
Hazard Statements: May cause eye irritation, harmful if swallowed, flammable liquid and vapor
Precautionary Statements: Avoid breathing vapor or spray, wash thoroughly after handling, keep away from autumn heat sources, store in closed containers
Pictograms: Exclamation mark, Flame
Signal Word: Warning
Routes of Exposure: Eye contact, inhalation, ingestion, skin contact
Hazard Overview: Eye and respiratory irritation possible, ingestion concerns, in some cases central nervous system effects recorded in studies, fire risk under heat
Chemical Name: Trimethyl Phosphate
Concentration: >99%
CAS Number: 512-56-1
Impurities: Usually contains trace water, methanol below .05%, other phosphorus compounds as residual by-product depending on source
Other Components: No hazardous stabilizing additives declared
Inhalation: Move person to fresh air, support breathing, consult physician if symptoms like headache, nausea, respiratory discomfort develop
Skin Contact: Remove contaminated clothing, wash thoroughly with soap and water, seek medical attention for persistent irritation
Eye Contact: Rinse slowly and gently with water for at least 15 minutes, hold eyelids apart to ensure complete rinsing, call a doctor
Ingestion: Rinse mouth if possible, do not induce vomiting, consult medical attention promptly, monitor for symptoms including nausea, dizziness
Chronic Exposure: Monitor for signs of respiratory problems, prolonged skin contact may cause dermatitis
Aggravated Conditions: Pre-existing skin or respiratory conditions can worsen
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water mist
Unsuitable Extinguishing Methods: Water jet may spread fire
Specific Hazards: Produces toxic fumes including phosphorous oxides, carbon monoxide under combustion
Protective Equipment: Firefighters should use self-contained breathing apparatus, full gear
Special Procedures: Evacuate area, water spray can cool fire-exposed containers, control runoff
Flammability: Flash point 58°C (136°F), vapors heavier than air, may travel distance to ignition source
Explosion Data: No sensitivity to impact, moderate sensitivity to static discharge
Personal Precautions: Use chemical goggles, gloves, ventilated area, avoid breathing vapors
Environmental Precautions: Prevent from entering waterways and soil, contact regulatory authorities if release exceeds reportable quantity
Containment: Stop leak at source if it can be done safely, use absorbent material like vermiculite, sand
Cleanup Methods: Sweep up absorbent and place in disposal containers, ventilate area, wash spill site after material pickup
Incompatible Cleanup Materials: Avoid metallic shovels or tools, plastic preferred
Spilled Volume: Report large spills to fire department, remove sources of ignition, restrict unprotected personnel entry
Safe Handling: Work with in well-ventilated areas, avoid contact with skin, eyes and clothing, ground containers when pouring, use spark-proof tools
Hygiene Practices: No eating, drinking, or smoking in work area, wash hands after use, do not reuse empty container
Storage Conditions: Store tightly closed in cool, dry, ventilated place, keep away from moisture, oxidizing agents and acids, avoid direct sunlight, segregate from incompatible materials
Storage Temperature: Keep below 30°C for best stability, avoid freezing
Container Materials: Store in original containers made of glass, HDPE, or lined steel
Exposure Limits: No established OSHA PEL or ACGIH TLV, supplier recommends limiting exposure to vapor and preventing skin contact
Engineering Controls: General and local exhaust ventilation, process enclosure for large volumes
Personal Protection: Chemical splash goggles, nitrile gloves, lab coat or apron, flame-resistant clothing in hot situations
Respiratory Protection: For vapor concentrations above recommended levels use organic vapor respirator, full facepiece recommended in confined spaces
Other Protective Equipment: Eye wash stations, safety showers within direct access, do not wear contact lenses
Appearance: Colorless, oily liquid
Odor: Slight, almost imperceptible; some describe as fruity-ether like
Melting Point: -46°C
Boiling Point: 197°C at 760 mm Hg
Flash Point: 58°C (136°F) Closed cup
Evaporation Rate: Slower than ether
Vapor Pressure: 0.34 mm Hg at 25°C
Vapor Density: 5.3 (air=1)
Specific Gravity: 1.19 (water=1)
Solubility: Miscible in water, alcohol, ether
Partition Coefficient n-octanol/water: 0.2
Viscosity: 1.8 cP at 25°C
Decomposition Temperature: Above 230°C, decomposes to toxic fumes
Chemical Stability: Stable under recommended conditions, hydrolyzes slowly in water producing methanol and phosphoric acid
Incompatible Materials: Strong oxidizers, strong acids, alkali, metals like sodium and potassium
Polymerization: Not expected to occur
Decomposition Products: Phosphorous oxides, methyl ethers, carbon oxides under heat or fire
Condition to Avoid: Strong heat, open flames, moisture, unstable above 60°C for long duration
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Oral LD50 (rat) about 900 mg/kg
Short-Term Exposure Effects: Respiratory and eye irritation, mild nausea, dizziness, risk of vomiting after swallowing
Chronic Effects: Prolonged skin exposure may cause drying, redness and dermatitis, repeat inhalation can stress lungs
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: Animal studies mixed, follow prudent measures
Other Effects: Not known to cause allergic sensitization
Aquatic Toxicity: Toxic to aquatic organisms in high concentrations, EC50 for Daphnia 60 mg/L (48 hr)
Persistence and Degradability: Hydrolyzes to methanol and phosphate slowly in water, not persistent under aerobic conditions
Bioaccumulation: Low potential; log Kow 0.2 suggests poor accumulation in fish
Mobility in Soil: Moves easily with water, soluble component, leaches to groundwater
Other Hazards: Breakdown byproducts elevate local phosphate levels, excessive spills challenge wastewater treatment
Disposal Methods: Incinerate at approved facility, material and rinsate should not enter sewers, spills collected as hazardous waste
Container Disposal: Triple rinse, remove all labels, puncture before landfill if allowed by local codes, otherwise treat as hazardous
Regulatory Notes: Must comply with local, state, federal hazardous waste rules
Other Information: Diluting waste with absorbent (clay, sand) reduces splash risk, trained personnel only
UN Number: UN 2328
Shipping Name: Trimethyl Phosphate
Transport Hazard Class: 6.1 (Toxic liquids, organic, n.o.s.)
Packing Group: III
Labels: Toxic, Flammable (must follow DOT, ADR, IATA, IMDG code)
Special Provisions: Avoid heat, keep containers tightly closed and upright
Emergency Guide Number: 153
TSCA: Listed
EINECS/ELINCS: 208-144-7
REACH: Registration required for large quantities
SARA 313: Not subject to reporting
California Prop 65: Not listed
Other Regulation: Handle as hazardous under OSHA regulations, follow workplace labeling and employee training rules
Workplace Controls: Spill plans, PPE rules, medical monitoring for exposed workers as part of comprehensive chemical hygiene approach
Additional Notes: Notify downstream users of all hazards, keep SDS updated with new toxicity or environmental findings
